REDUCES MENSTRUAL PAIN
CONTRIBUTES TO RELAXATION AND REST
HELPS SUPPORT OVERALL IMMUNITY

Levagen+: this is high-quality palmitoylethanolamide (PEA). PEA is biologically produced by our body through a repair mechanism, acting on CB1, CB2 and GPR55 receptors as well as on the TRPV1 channel.

It is a natural anti-inflammatory with clear advantages in various fields of application. Thanks to the use of lipisperse technology, the ingredient is dispersible, increasing its bioavailability (1.75 more than the standard Levagen version).

HOW DOES IT WORK ?

The main mechanism of action is binding to PPAR-a, which provides anti-inflammatory, analgesic and neuroprotective properties. It also has an indirect influence on the endocannabinoid system (ECS) by inhibiting the enzyme acid-fat amide-hydrolase (FAAH) and increasing levels of anandamide (also known as the ‘bliss’ molecule).

On the immune side, PEA inhibits mast cell degradation and modulates cytokines

Study duration: Randomized, placebo-controlled, double-blind, crossover study of 16 weeks.

Participants: 80 healthy women aged 18 and over, who had experienced at least four menstrual cramps in the last six menstrual cycles and had taken at least one dose of an over-the-counter analgesic medication for effective pain relief.

Results: Levagen®+ significantly reduced pain scores 1h, 1.5h, 2h and 2.5h after administration compared with placebo, with no adverse effects.

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