REDUCES JOINT PAIN AND INFLAMMATION
IMPROVES MUSCLE RECOVERY
IMPROVES SLEEP QUALITY
SUPPORTS IMMUNE RESPONSE
REDUCES MIGRAINES

Levagen+: this is high-quality palmitoylethanolamide (PEA). PEA is biologically produced by our body through a repair mechanism, acting on CB1, CB2 and GPR55 receptors as well as on the TRPV1 channel.

It is a natural anti-inflammatory with clear advantages in various fields of application. Thanks to the use of lipisperse technology, the ingredient is dispersible, increasing its bioavailability (1.75 more than the standard Levagen version).

HOW DOES IT WORK ?

The main mechanism of action is binding to PPAR-a, which provides anti-inflammatory, analgesic and neuroprotective properties. It also has an indirect influence on the endocannabinoid system (ECS) by inhibiting the enzyme acid-fat amide-hydrolase (FAAH) and increasing levels of anandamide (also known as the ‘bliss’ molecule).

On the immune side, PEA inhibits mast cell degradation and modulates cytokines

Conclusion d’une étude clinique en double aveugle contre placebo
– 120 SUJETS RÉPARTIS EN 3 GROUPES –

Reduction of acute joint pain (175 mg/day)

74 participants, 2 weeks
– Levagen reduces joint pain in only 3 days
– Levagen improves quality of life

Recovery from muscular exercise (167.5mg/day)

28 men, age 18-35
Levagen+ was statistically significant (compared with placebo) for :
– lower myoglobin levels after exercise
– decrease in blood lactate concentration after exercise
– increased levels of protein kinase B
(mTOR) levels associated with resistance training

Acute muscle pain reduction (350 mg/day)

120 patient study, WOMAC score
Levagen® supports people with symptoms of mild to moderate osteoarthritis in the following ways:
– improved total WOMAC score
– reduced pain
– reduced stiffness
– improved joint function

Improved sleep quality (350 mg/day)

125 Healthy adults , 350mg 1h before sleep 
Levagen shows results from 2 weeks onwards for :
– reducing the time needed to fall asleep
– reducing the time needed to feel awake in the morning
– improve cognitive function on waking

Reduction of allergic rhinitis (350 mg/day)

101 adults for 2 weeks
– Levagen lowers blood histamine levels
– Levagen reduces symptoms of allergic rhinitis

Migraine reduction (525 mg/day)
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